Profhilo, Sunekos or Polynucleotides: Which skin booster is right for you?

16 / 10 / 2026

Profhilo, Sunekos or Polynucleotides: Which skin booster is right for you?

Skin boosters have become hugely popular for people who want healthier, more radiant skin without changing the shape of their face. But with names like Profhilo, Sunekos and polynucleotides, it can be hard to know the difference. Here is a simple guide to the skin boosters we offer at Castle Street.

What is a skin booster?

Unlike dermal fillers, skin boosters do not add volume or change your features. Instead, they improve the quality of your skin itself: its hydration, firmness, texture and glow. They are a lovely option if you feel your skin looks tired, dull or is starting to lose its bounce.

Profhilo

Profhilo is a highly concentrated hyaluronic acid treatment that spreads through the skin after the application process. It deeply hydrates and stimulates your skin to produce more collagen and elastin, improving firmness and early laxity across a broad area.

• Best for: overall skin quality, hydration and early signs of sagging on the face and neck.
• Treatment: usually two sessions, four weeks apart, with results lasting around six months.
• Price: £275 per session

Sunekos

Sunekos combines hyaluronic acid with amino acids, the building blocks your skin uses to make its own collagen and elastin. It works to regenerate the skin from within, improving hydration, firmness and fine lines.

• Best for: delicate areas such as under the eyes, as well as the face, neck and décolletage.
• Treatment: a course of sessions, with results building gradually.
• Price: from £250 per area per session

Polynucleotides

Polynucleotides use purified DNA fragments to support the skin’s natural repair processes. They are particularly helpful for skin affected by sun damage, scarring or fine lines, and are often used around the eyes.

• Best for: skin repair, fine lines, crepey skin and the under-eye area.
• Treatment: a course of sessions, with results building over several weeks.
• Price: £295 per session

Which one should I choose?

Every patient’s skin is different, and sometimes a combination works best. At your consultation, we look at your skin, talk about what bothers you and recommend the treatment most likely to give you the result you want.

Is there any downtime?

Most people have some small raised bumps or mild redness for a few hours after treatment, and occasionally a little bruising. Most patients go straight back to their day.

Book a consultation

A facial aesthetics consultation costs £50, redeemable against treatment. Call us on 01494 527 971 to book.